Aproxi 80 Aprepitant Ifosfamide
ModerateAprepitant is a CYP3A4 inhibitor, which means it can slow down the CYP3A4 enzyme in your body. Your body uses this enzyme to turn Ifosfamide into its active alkylating form, the part that actually works against the cancer. If aprepitant slows this step, less of the active form may be made, and Ifosfamide might not work as well as it should.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.