Topirva 50 Topiramate Linagliptin + Metformin Hydrochloride
ModerateTaking topiramate with linagliptin and metformin can cause problems because topiramate frequently lowers serum bicarbonate levels. This can lead to non-anion gap, hyperchloremic metabolic acidosis.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.