Rivanex 10 Rivaroxaban Dronedarone
MajorTaking Rivaroxaban together with Dronedarone, a combined P-gp and CYP3A4 inhibitor, increases Rivaroxaban exposure and its effects (factor Xa inhibition and PT prolongation). This is why taking these two medicines together should be avoided.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.