XARELTA 2.5 Rivaroxaban Phenytoin
MajorTaking Rivaroxaban together with Phenytoin, a combined P-gp and strong CYP3A4 inducer, decreases how well Rivaroxaban works and should be avoided.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.