Cognium 10 Methylphenidate Hydrochloride Fosphenytoin Sodium
ModerateMethylphenidate can raise the level of phenytoin in your blood. Fosphenytoin Sodium is changed into phenytoin inside the body, so this matters when you take the two together. Other medicines and substances that can also push phenytoin levels up include a single bout of heavy drinking, amiodarone, chloramphenicol, chlordiazepoxide, cimetidine, diazepam, dicumarol, disulfiram, estrogens, ethosuximide, fluoxetine, H2-antagonists, halothane, isoniazid, phenothiazines, phenylbutazone, salicylates, succinimides, sulfonamides, tolbutamide and trazodone. Ask your doctor or pharmacist before you combine methylphenidate with fosphenytoin.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.