Atolimus Tacrolimus Palbociclib
ModeratePalbokin (Palbociclib) can raise the level of Tacrolimus in your body. Tacrolimus is a CYP3A substrate with a narrow therapeutic index, which means even a small rise in its level can matter. Your doctor may need to lower the Tacrolimus dose when the two are used together. Other medicines in this same group include Alfentanil, Cyclosporine, Dihydroergotamine, Ergotamine, Everolimus, Fentanyl, Pimozide, Quinidine and Sirolimus.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.