Opegus Ribavirin Peginterferon alfa-2a [Pegylated Interferon alfa-2a]
ModerateWhen peginterferon alfa-2a [pegylated interferon alfa-2a] is taken with ribavirin, medicines broken down by CYP1A2 need watching. Theophylline levels may rise, so its dose may need adjusting. Methadone should be watched for signs of toxicity. With nucleoside analogues, watch closely for toxicity, and lower or stop one or both medicines if it gets worse. Zidovudine may worsen neutropenia or anemia. Azathioprine is also listed.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.