Roxarel 15 Rivaroxaban Ritonavir
MajorTaking Rivaroxaban with Ritonavir, a combined P-gp and CYP3A4 inhibitor, increases the level of Rivaroxaban in the body and its effects (factor Xa inhibition and PT prolongation). You should avoid taking these two medicines together.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.