Aromatin Anastrozole Warfarin Sodium
MinorIn a study of 16 healthy male volunteers, Anastrozole did not change how much warfarin the body was exposed to, as measured by Cmax and AUC. It also did not change warfarin's blood-thinning effect, as measured by prothrombin time, activated partial thromboplastin time and thrombin time. This held for both forms of warfarin, R-warfarin and S-warfarin.
Little or no effect is expected. You usually do not need to change anything, but still tell your doctor or pharmacist about every medicine you take.