Sunitix Sunitinib Itraconazole
ModerateItraconazole can raise the level of Sunitinib in your blood. This happens because Itraconazole blocks CYP3A4, a liver enzyme that helps break Sunitinib down. When the enzyme is blocked, Sunitinib stays in the body at a higher level than usual. Ketoconazole, Clarithromycin, Ritonavir and Voriconazole act on the same enzyme in the same way.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.