Prasugrel Hydrochloride (Appras) can be taken together with aspirin at a daily dose of 75 mg to 325 mg. It can also be taken with heparin, GPIIb/IIIa inhibitors, statins and digoxin. The same goes for medicines that reduce stomach acid, including proton pump inhibitors and H2 blockers.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.