Naproxen-500 Naproxen Naproxen Sodium + Esomeprazole Magnesium
MinorTaking naproxen and esomeprazole with high-fat food does not change how much naproxen the body absorbs, but it delays peak levels (tmax) by 10 hours and reduces peak blood concentration (Cmax) by about 12%.
Little or no effect is expected. You usually do not need to change anything, but still tell your doctor or pharmacist about every medicine you take.