Tacrolim Tacrolimus Crizotinib
MajorYou should avoid taking crizotinib at the same time as tacrolimus, because tacrolimus is a CYP3A substrate with a narrow therapeutic index.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.