DEU-20 Omeprazole Clopidogrel Bisulphate
MajorTaking clopidogrel with NSAIDs, warfarin, or SSRIs and SNRIs increases the risk of bleeding. Avoid taking clopidogrel together with omeprazole, esomeprazole, or other CYP2C19 inhibitors. Avoid taking clopidogrel with repaglinide (CYP2C8 substrates), as it increases blood levels of repaglinide.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.