Hypnocum Midazolam Treosulfan
ModeratePhysiologically-based pharmacokinetic (PBPK) modeling with the sensitive index substrates midazolam, omeprazole, and digoxin for CYP3A4, CYP2C19, and P-gp predicted a weak interaction (AUC ratio ≥1.25 and <2) for CYP3A4, and CYP2C19, and a negligible (AUC ratio <1.25) interaction for P-gp.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.