Epleron Eplerenone Trimethoprim
ModerateTaking eplerenone with trimethoprim may raise the potassium level in your blood (hyperkalaemia). The same risk applies with ACE inhibitors, angiotensin receptor blockers, ciclosporin and tacrolimus.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.