Dexibuprofen leaflet says problems can show up when it is used at the same time with many medicines. The list includes digoxin, which is why this pair needs care. The others named are anticoagulants (blood thinners), hydantoins, sulfonamides, ticlopidine, lithium, other NSAIDs, ACE inhibitors, beta blockers, cyclosporine, tacrolimus, corticosteroids, methotrexate, pentoxifylline, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, thiazide and thiazide-type diuretics, and zidovudine.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.