Elzer Donepezil Hydrochloride Phenobarbital
ModeratePhenobarbital can make donepezil work less well. If you take both, donepezil may not control memory and thinking problems as well as it should. Tell your doctor before you start or stop phenobarbital, because your donepezil dose may need to be reviewed.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.