Octafen Ketoprofen Cyclosporine
ModerateKetoprofen is an NSAID, and taking it with cyclosporin needs care. The two together can push the potassium level in your blood too high (hyperkalemia). The same risk applies to other medicines that raise potassium: potassium salts, potassium-sparing diuretics, ACE inhibitors, angiotensin II antagonists, other NSAIDs, heparins (low molecular-weight or unfractioned), tacrolimus and trimethoprim. Taking several of these at the same time makes the risk higher. Cyclosporin with ketoprofen also raises the chance of kidney damage (nephrotoxicity). If you use both, your doctor should decide whether it is safe for you. Do not start or stop either one on your own.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.