Xynofen Ketoprofen Trimethoprim
ModerateTaking ketoprofen (an NSAID) together with trimethoprim can increase the risk of hyperkalemia. The risk of hyperkalemia can also rise with ACE inhibitors and angiotensin II antagonists.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.