Trimethoprim Trimethoprim Lamivudine + Zidovudine + Nevirapine
ModerateTaking sulfamethoxazole or trimethoprim with lamivudine, zidovudine, and nevirapine can decrease the clearance and increase the AUC of this medicine. This can lead to higher levels and increased effects of lamivudine, zidovudine, and nevirapine in your body.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.