Taking adefovir dipivoxil (Virodip) with ibuprofen 800 mg three times daily raised adefovir Cmax by 33%, AUC by 23% and urinary recovery, because adefovir's oral bioavailability was higher.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.