Snow Famotidine Deucravacitinib
MinorIn clinical trials, Deucravacitinib was taken together with several other medicines. None of them made a clinically significant difference to how the body handles Deucravacitinib. The medicines tested were cyclosporine (blocks both Pgp and BCRP), fluvoxamine (blocks CYP1A2), ritonavir (listed as a CYP1A2 inducer), diflunisal (blocks UGT 1A9), pyrimethamine (blocks OCT1), famotidine (an H2 receptor antagonist) and rabeprazole (a proton pump inhibitor). So in these trials, taking famotidine with Deucravacitinib did not meaningfully change how the body handles Deucravacitinib.
Little or no effect is expected. You usually do not need to change anything, but still tell your doctor or pharmacist about every medicine you take.