Indications
Vildagil is used together with a proper diet and regular exercise to help control blood sugar in adults with type 2 diabetes. It can be taken alone, or alongside Metformin, a Sulphonylurea, a Thiazolidinedione, or Insulin, when diet, exercise, and a single anti-diabetic medicine are not enough to keep blood sugar levels adequately under control.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. In people with type 2 diabetes, it is thought to work by slowing the breakdown of incretin hormones. Incretin hormones, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine throughout the day, with levels rising after a meal. These hormones are quickly broken down by the enzyme DPP-4. Incretins are part of the body's own system for regulating glucose balance. When blood glucose levels are normal or high, GLP-1 and GIP boost insulin production and release from the beta cells of the pancreas through intracellular signaling pathways involving cyclic AMP. GLP-1 also reduces glucagon release from the pancreas's alpha cells, which lowers glucose production by the liver. By raising and extending the levels of active incretins, vildagliptin increases insulin release and lowers glucagon levels in the blood, acting in a glucose-dependent manner.
Pregnancy & Breastfeeding
Vildagliptin should not be used in pregnancy. Vildagliptin should not be used during lactation.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.