Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Valpress is used to treat high blood pressure (hypertension). In people with congestive heart failure, it helps reduce the need for hospital admission. It is also used to lower the risk of death in people who have developed congestive heart failure after a heart attack (myocardial infarction).

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Valsartan is an oral medication belonging to a class of drugs called angiotensin receptor blockers (ARBs). It is orally active and acts as a specific angiotensin II antagonist at the AT1 subtype. When angiotensin attaches to these receptors, blood vessels narrow (vasoconstrict), which raises blood pressure (hypertension). Valsartan blocks the angiotensin II receptor, and by blocking this action, it dilates blood vessels and lowers blood pressure without affecting pulse rate. Valsartan has a much greater affinity (about 20,000 fold) for the AT1 receptor than for the AT2 receptor, and it does not bind or block other hormone receptors or ion channels known to be important in cardiovascular regulation.

Pregnancy & Breastfeeding

Pregnancy: Valsartan should not be used during pregnancy, as it can injure or even cause death to the fetus if taken in the 2nd or 3rd trimester. If pregnancy is detected while taking this medicine, Valsartan should be stopped as soon as possible.

Nursing mothers: It is not known whether Valsartan passes into human breast milk. Because of the potential for adverse effects in the nursing infant, a decision should be made whether to stop breastfeeding or stop the medicine, taking into account how important it is for the mother.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Hypertension: The usual dose of Valsartan is 80 to 160 mg once daily. The maximum dose is 320 mg daily. The full blood pressure lowering effect is reached within 4 weeks. Heart failure: The usual dose is 40 mg twice daily, which may be increased to 80 to 160 mg twice daily. After a heart attack (post-myocardial infarction): The starting dose is 20 mg twice daily. The dose should be increased towards a target of 160 mg daily, provided it is tolerated without side effects.

Side Effects & Interactions