Indications
Mydrimide sterile eye drops are used to dilate (widen) the pupil so that the doctor can see into the back of the eye. They are used before eye examinations, such as cycloplegic refraction and examination of the fundus (the back of the eye). Mydrimide eye drops may also be used before and after eye surgery.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Tropicamide, which is to some extent structurally related to atropine, induces mydriasis and cycloplegia through paralysis of the parasympathetic system. Tropicamide is a parasympatholytic agent, which acts by blocking the action of the parasympathetic nervous system. As acetylcholine is the neurotransmitter at the receptor site of the parasympathetic nervous system, tropicamide competes with acetylcholine for uptake at the receptor sites, thereby blocking its action. The results are mydriasis, due to unopposed action of the dilator pupillae, and cycloplegia.Tropicamide visibly dilates the pupil after 5 minutes. It reaches its maximum diameter after 20-25 minutes and returns to its normal size within approx. 6 hours. The onset of the effect is rapid, but it disappears 45-60 minutes after the last instillation. The best time for retinoscopy is therefore approximately 20 minutes after the instillation of the last drop.
Pregnancy & Breastfeeding
Pregnancy Category C. Tropicamide should be used during pregnancy only when clearly needed. Whether it passes into human breast milk is not known, so caution is advised when it is used by a breastfeeding woman, since many drugs do pass into breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.