Indications
Timotor is indicated for the treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS), as well as for the treatment of postoperative paralytic ileus, to accelerate the resumption of intestinal transit following abdominal surgery.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Trimebutine Maleate is a noncompetitive spasmolytic. It has a moderate affinity for opiate receptors and shows marked anti-serotonin activity, particularly at 'mu' receptors. In isolated guinea pig strips of colon and ileum, it regulates spontaneous activity and improves synchronization between electrophysiological spikes and contractions. It does not alter normal motility but works to regulate abnormal intestinal activity.
Pregnancy & Breastfeeding
Although teratological studies have not found any drug-related adverse effects on the course or outcome of pregnancy, Trimebutine Maleate is not recommended for use in pregnant women. Whether it passes into breast milk is not known. During breastfeeding, it should be used only if the potential benefit to the mother outweighs the possible risk to the nursing infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.