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Community data Updated 2 months ago

Theophylline

Bronchodilator Prescription
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Indications

Asthma Chronic Obstructive Pulmonary Disease Bronchitis

Asmaloc SR is indicated for the control of acute asthma; the management of chronic asthma, for both symptomatic and prophylactic treatment; the control of nocturnal asthma and early morning wheezing; the management of chronic obstructive lung disease (chronic bronchitis and emphysema) and acute exacerbation of chronic obstructive lung disease; and the control of apnea of prematurity.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Theophylline is a bronchodilator belonging to the methylxanthine class of drugs. In patients with reversible airway obstruction, it works in two distinct ways: it relaxes the smooth muscle of the airways and it reduces the airways' responsiveness to irritating stimuli. It also strengthens the contraction of the diaphragm muscles. Theophylline's half-life varies depending on several known factors; in adult nonsmokers with uncomplicated asthma, it typically ranges from 3 to 9 hours.

Pregnancy & Breastfeeding

Pregnancy: It isn't known whether theophylline can harm an unborn baby, so xanthine medicines like this one should be used during pregnancy only when clearly necessary.

Breastfeeding: Theophylline passes into breast milk and may make a nursing infant irritable or show other mild signs of toxicity. Serious harm to the baby is unlikely unless the mother's blood theophylline level is itself too high.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Theophylline dosing must be tailored to each person, guided by measurements of peak theophylline levels in the blood, so that the dose gives the greatest possible benefit with the least risk of side effects. Most sustained release products can be taken every 12 hours in adults, although some children whose livers break down theophylline unusually fast may need a dose every 8 hours. The recommended maintenance doses within the accepted therapeutic range are as follows. For those aged 16 years or older, 10 mg per kg per day, not exceeding 900 mg per day. For ages 12 to 15 years, 13 mg per kg per day. For ages 9 to 11 years, 16 mg per kg per day. For ages 1 to 8 years, 24 to 24 mg per kg per day. For ages 6 months to 1 year, 12 to 18 mg per kg per day. For ages 1 to 6 months, 10 mg per kg per day. Regarding use in children, theophylline is cleared from the body very slowly in newborns. In pediatric patients, doses must be chosen with great care and blood theophylline levels must be monitored closely.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.