Indications
Inoten helps relieve pain and inflammation in a range of musculoskeletal conditions, including rheumatoid arthritis, osteoarthritis, arthrosis, and ankylosing spondylitis. It is also used for extra-articular conditions such as tendinitis, bursitis, and periarthritis of the shoulder (shoulder-hand syndrome) or hip, as well as strains, sprains, and acute gout.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties, and it also inhibits platelet aggregation. It works by inhibiting prostaglandin biosynthesis. In-vitro tests of leukocyte peroxidase suggest that Tenoxicam may act as a scavenger for active oxygen at the site of inflammation. It is also a potent in-vitro inhibitor of the human metalloproteinases stromelysin and collagenase, enzymes that drive cartilage breakdown. Together, these effects help explain the therapeutic benefit of Tenoxicam in treating painful inflammatory and degenerative disorders of the musculoskeletal system. In animal studies, Tenoxicam showed no mutagenic, carcinogenic or teratogenic effects. However, as with other prostaglandin inhibitors, animal safety studies noted renal and gastrointestinal effects, along with an increased incidence of dystocia and delayed parturition.
Pregnancy & Breastfeeding
NSAIDs inhibit prostaglandin synthesis and, when used late in pregnancy, may cause premature closure of the fetal ductus arteriosus, prolong labor and delay delivery. Treatment during the third trimester should be avoided. Single-dose studies show that only a very small amount of tenoxicam, about 0.2 percent, passes into breast milk, and no adverse effects have been reported in breast-fed infants of mothers taking Tenoxicam. Even so, infants should be weaned or the drug discontinued.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.