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Community data Updated 2 months ago

Sucralfate

Chelating complex Prescription
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Indications

Peptic Ulcer

Ralfate is indicated in adults and adolescents over 14 years of age for the treatment of duodenal ulcer, gastric ulcer and chronic gastritis, and for the prevention of gastrointestinal bleeding from stress ulceration in seriously ill patients.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Sucralfate is considered non-systemic, since only a tiny fraction of the drug is absorbed from the gastrointestinal tract, and that fraction is mostly excreted in the urine. It works by forming a chemical complex that binds to the site of a gastric or duodenal ulcer, creating a protective barrier over it and allowing the ulcer to heal. It also works by blocking the action of pepsin and bile.

Pregnancy & Breastfeeding

Safety in pregnant women hasn't been established, so Sucralfate should only be used during pregnancy if it's clearly needed. It's also not known whether this medicine passes into human breast milk, so breastfeeding mothers should use it with caution.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Duodenal ulcer, gastric ulcer and chronic gastritis. Adults: the usual dose is 2 g of Sucralfate twice daily, taken on rising and at bedtime, or 1 g four times a day, taken 1 hour before meals and at bedtime. The maximum daily dose is 8 g, though treatment for up to twelve weeks may be needed in resistant cases. Children: the safety and efficacy of Sucralfate in children under 14 years of age have not been established. Elderly: there are no special dosage requirements for elderly patients, but as with all medicines the lowest effective dose should be used. Prevention of gastrointestinal bleeding from stress ulceration. Adults: the usual dose is 1 g of Sucralfate, given by mouth or through a nasogastric tube, 4 to 6 times a day. To prevent the nasogastric tube from clogging, flush it with 10 ml of water after each dose. The length of preventive treatment must be decided for each patient. Treatment should continue for as long as one or more risk factors for stress ulceration remain, but normally for no more than 14 days. Sucralfate should be taken on an empty stomach. Antacids should not be given within 30 minutes of a Sucralfate dose.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.