Sodium Fusidate

Indications

Pneumonia Sepsis

Fucimax tablet is used to treat staphylococcal infections, whether localised or generalised. Examples include abscesses, furunculosis (boils), wound infections, pneumonia, peritonitis, osteomyelitis, septicaemia, enteritis and ear, nose and throat infections. In severe or deep-seated infections, infections caused by methicillin-resistant Staphylococci, or where prolonged treatment may be needed, Fucimax must be given together with another anti-staphylococcal antibiotic.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Sodium Fusidate is the sodium salt of fusidic acid, an antibiotic obtained from the fungus Fusidium coccineum. It works by inhibiting protein synthesis, preventing translocation on the ribosome. After oral or parenteral administration, it reaches concentrations sufficient for bactericidal activity against Staphylococci in pus, exudate, soft tissue, bone tissue, synovial fluid, aqueous humour, vitreous body, burn crusts, intracranial abscess, sputum and serum.

Pregnancy & Breastfeeding

Pregnancy Category C. In reproduction studies, mating frequency and fertility were normal, and offspring showed no abnormal changes. As a precaution, systemic Sodium Fusidate is best avoided during pregnancy.

Lactation: Safety during lactation has not been established. Sodium Fusidate is known to cross the placental barrier and can be detected in human breast milk. Mothers who wish to breastfeed should therefore use it with caution.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For staphylococcal skin infections, adults and children aged 12 years and above take 250 mg 2 times a day for 5 to 10 days. For penicillin-resistant staphylococcal infections such as osteomyelitis, pneumonia, septicemia, wound infections, endocarditis and superinfected cystic fibrosis, adults and children aged 12 years and above take 500 mg 3 times a day. For severe infections the dose can be increased to 1 gram 3 times a day. With the oral suspension, children aged 1 to 11 months take 15 mg/kg 3 times a day, children aged 1 to 4 years take 250 mg 3 times a day, children aged 5 to 11 years take 500 mg 3 times a day, children aged 12 to 17 years take 750 mg 3 times a day, and adults take 750 mg 3 times a day. No dosage adjustment is necessary in the elderly. Since Sodium Fusidate is excreted in the bile, no dosage modification is needed in patients with renal impairment. No dosage adjustment is required in patients undergoing haemodialysis, as the drug is not significantly dialysed.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.

Key Interactions

Checker →

Cyclosporine