Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Sodinate is indicated in-1. Management of acidosis in cardiac arrest. 2. Alkalinization of urine.3. Management of metabolic acidosis in: Severe renal disease Uncontrolled diabetes Circulatory insufficiency from shock or dehydration Severe primary lactic acidosis

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Sodium bicarbonate acts as a systemic alkalizer: it raises plasma bicarbonate levels, buffers excess hydrogen ions, and increases blood pH, helping to reverse the clinical signs of acidosis. As a urinary alkalizer, it boosts the excretion of free bicarbonate ions in the urine, raising urinary pH. In cases of severe diarrhea, where bicarbonate loss can be substantial, it also helps restore the resulting electrolyte imbalance.

Pregnancy & Breastfeeding

Use during pregnancy only if the potential benefit outweighs the potential risk to the developing baby. In pregnant women, animal studies have shown adverse effects on the kidneys, so this medicine is not recommended during the second and third trimesters. It may also make high blood pressure worse. This medication can pass into breast milk.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Oral: The usual dose is 300 mg to 2 grams, taken 1 to 4 times daily. Intravenous, for severe metabolic acidosis: In adults, it is given by slow injection as a hypertonic solution of up to 8.4% (1000 mmol/L), or by continuous infusion of a weaker solution, usually 1.26% (150 mmol/L). To correct acidosis during advanced cardiac life support procedures, 50 ml of an 8.4% solution may be given. In elderly patients, dosage adjustments may be required.

Side Effects & Interactions