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Community data Updated 2 months ago

Roxithromycin

Macrolides Prescription
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Indications

Chronic Obstructive Pulmonary Disease Pneumonia Bronchitis Sinusitis Pharyngitis Tonsillitis Skin and Soft Tissue Infection Otitis Media Eczema

Ryth is used to treat infections caused by susceptible microorganisms. These include respiratory infections such as pneumonia, acute and chronic bronchitis, and bronchopneumonia, as well as ENT infections such as tonsillitis, pharyngitis, sinusitis and otitis media. It is also used for skin infections such as folliculitis, furuncles, cellulitis, carbuncles, pyoderma, impetigo and infected dermatitis, and for genital infections such as urethritis, prostatitis, cervicitis and salpingitis, especially when caused by Chlamydia trachomatis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Roxithromycin works by attaching to the 50s subunit of the bacterial ribosome, and this binding does not reverse. In doing so, it interferes with the transpeptidation and translocation steps that susceptible bacteria need to build proteins. Protein synthesis is thereby blocked, and the bacteria's growth is slowed as a result.

Pregnancy & Breastfeeding

Pregnancy: Safety in pregnancy has not been established for Roxithromycin.

Breastfeeding: Small amounts pass into breast milk, but this has not been shown to cause adverse effects in breastfed infants.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Adult dose: The usual adult dose is one 300 mg tablet once daily, or one 150 mg tablet twice a day, continued for at least two days after symptoms have resolved. A normal course of treatment lasts between 5 and 10 days. Roxithromycin is best taken on an empty stomach. In severe hepatic impairment, the dose is 150 mg once daily. Pediatric dose: The dose for children is 2.5 to 5 mg/kg of body weight twice a day. The following general guidelines may be followed: children weighing 6 to 11 kg, 25 mg of Roxithromycin every 12 hours; 12 to 23 kg, 50 mg every 12 hours; 24 to 40 kg, 100 mg every 12 hours. A normal course of treatment lasts between 5 and 10 days.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.