Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Rifaxin is indicaed in- Treatment of traveler's diarrhea by noninvasive strains of E. coli reduction in risk of overt hepatic encephalopathy bacterial overgrowth of irritable bowel syndrome.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic. Very little of the drug will pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. Rifaximin inhibits bacterial RNA synthesis by its action on the beta-subunit of the DNA-dependent RNA polymerase. It shows the same broad spectrum activity as rifamycin which exerts bactericidal action against many species of Gram-positive and Gram-negative, aerobic and anaerobic bacteria.

Pregnancy & Breastfeeding

Pregnancy category C. It is not known whether rifaximin passes into human breast milk.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Traveler's diarrhea (patients 12 years and older): 200 mg by mouth 3 times a day for 3 days. Hepatic encephalopathy (patients 18 years and older): 550 mg by mouth 2 times a day. Bacterial overgrowth in irritable bowel syndrome: 400 mg by mouth 3 times a day for 10 days, or 550 mg by mouth 3 times a day for 14 days. May be taken with or without food.