Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Repanid is used alongside diet and exercise to lower blood glucose in people with type 2 diabetes mellitus (NIDDM) whose high blood sugar is not adequately controlled by diet and exercise alone. Repanid is also used together with Metformin to lower blood glucose in people whose high blood sugar cannot be controlled by exercise, diet, and either Repanid or Metformin on its own.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Repaglinide attaches to specific receptors on the cell membrane, prompting ATP-dependent K+ channels to close and the membrane to depolarise. This allows Ca++ to flow into the cell, raising intracellular Ca++ levels and triggering the release of insulin.

Pregnancy & Breastfeeding

Safety in pregnant women has not been established. Repaglinide should be used during pregnancy only if it is clearly needed. It is not known whether Repaglinide is excreted in human milk. Because many drugs are excreted in human milk, and because nursing infants could face serious adverse reactions from Repaglinide, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For patients who have not been treated before, or whose HbA1c is below 8%, the starting dose should be 0.5 mg before each meal. For patients previously treated with blood glucose-lowering drugs and whose HbA1c is above 8%, the initial dose is 1 or 2 mg before each meal. Repaglinide should be taken immediately before each meal, or up to 30 minutes beforehand. The dose should be adjusted according to response at intervals of 1 to 2 weeks. Up to 4 mg may be given as a single dose, with a maximum of 16 mg daily.

Side Effects & Interactions