Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Delentin is used to treat infections caused by roundworm (Ascaris lumbricoides), pinworm (Enterobius vermicularis), hookworm (Ancylostoma duodenale and Necator americanus), and Trichostrongylus. It can be given to both adults and children, whether one of these parasites is present or several occur together.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Pyrantel pamoate works by causing a sudden, spastic contraction of the worm's muscles that then locks into paralysis. This makes the worm release its grip on the intestinal wall, so it is simply carried out of the body in the stool through the gut's normal movements. Because very little of the drug crosses into the bloodstream from the intestine, the small doses used do not go on to affect the person taking it.

That said, spastic paralyzing agents like pyrantel pamoate can, in a heavy worm infestation, cause a complete intestinal blockage. This tends to happen as a worm impaction, when a small body with a very high worm burden is treated and has to pass a large number of dislodged worms all at once. Usually, though, the worms simply pass in the stool or with some diarrhea, straining, and occasionally vomiting.

Pregnancy & Breastfeeding

Pregnancy: There is no established safety data for Pyrantel Pamoate use during pregnancy, so it is generally not advised for pregnant patients. It is also not recommended for children under 1 year of age.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Pyrantel Pamoate can be taken by mouth at any time, with or without food. The usual approach is a single dose of 11 mg/kg body weight, up to a maximum of 1 g, to treat the infestations noted above. For Pinworm infection, it is often advisable to repeat this dose after 2 weeks.