Indications
P-caine sterile eye drops are used when a topical anaesthetic for the eye is needed. They provide short-lasting numbing of the cornea for procedures such as tonometry (measuring eye pressure), gonioscopy, removal of foreign bodies from the cornea, and other brief procedures on the cornea and conjunctiva.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
The main site of anesthetic action is the nerve cell membrane, where proparacaine interferes with the large, transient increase in membrane permeability to sodium ions that is normally produced by a slight depolarization of the membrane. As the anesthetic action gradually develops within a nerve, the threshold for electrical stimulation progressively rises and the safety factor for conduction declines; once this action is sufficiently developed, conduction is blocked. Several studies suggest that local anesthetics may limit sodium ion permeability by closing the pores through which these ions migrate within the lipid layer of the nerve cell membrane.
Pregnancy & Breastfeeding
Pregnancy Category C. No animal reproduction studies have been carried out with Proparacaine Hydrochloride sterile eye drops 0.5%, and it is not known whether the drug can harm the fetus or affect fertility when given to a pregnant woman. For this reason, it should be used in pregnancy only if there is a clear need.
Breastfeeding: It is not known whether Proparacaine Hydrochloride passes into human breast milk. Since many drugs do pass into breast milk, it should be used with caution in nursing mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.