Indications
Diatus is used alongside diet and exercise to improve blood sugar (glycaemic) control in patients with type II diabetes (NIDDM). It may be given on its own, or in combination with a sulphonylurea, Metformin or Insulin when diet and exercise together with the single agent do not give adequate glycaemic control.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Pioglitazone belongs to a relatively new class of oral anti-diabetic drugs known as thiazolidinediones. It works only when insulin is present in the body, as its action depends on insulin being available. The drug lowers insulin resistance in both peripheral tissues and the liver, which leads to greater insulin-dependent uptake of glucose and a reduction in the liver's glucose output. Pioglitazone also helps correct abnormal lipid metabolism by activating a receptor called peroxisome proliferator-activated receptor gamma (PPAR-γ).
Pregnancy & Breastfeeding
During Pregnancy and Breastfeeding: Well-controlled studies looking at Pioglitazone's safety in pregnant women are lacking, so it should only be used during pregnancy if the expected benefit to the mother outweighs any possible risk to the unborn baby. For lactation, it is not known whether Pioglitazone passes into human breast milk; since many medicines do pass into breast milk, breastfeeding mothers should not take it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.