Indications
Remathrin cream is indicated for the treatment of scabies and crab lice infestations (Pediculosis). Scabies can affect everyone in the family. If one is infected, all family members must be treated together.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Permethrin cream contains permethrin, a pyrethroid compound used topically to treat infestation with Sarcoptes scabiei (scabies). It works on the nerve cell membrane of the parasite, disrupting the sodium channel current that normally regulates the membrane's polarization. This disturbance delays repolarization and leads to paralysis of the mites.
Pharmacokinetics: Topical application is the only approved route of administration, and human data on systemic exposure or kinetics after skin application remain limited. Some metabolism takes place in the skin before absorption. Less than 0.5% of the applied dose is absorbed within the first 48 hours. Once absorbed, permethrin is rapidly broken down through ester hydrolysis, most likely in the liver, and the resulting products are excreted mainly in the urine.
Pregnancy & Breastfeeding
Pregnancy: No specific studies have looked at permethrin use during pregnancy, so it should only be used if a doctor advises it.
Breastfeeding: It isn't known whether permethrin passes into breast milk, so breastfeeding mothers should avoid using it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.