Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago

Pentazocine

Opioid analgesics Prescription
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Indications

Pain

Pentazo helps relieve moderate to severe pain. Doctors may also give it before surgery to help patients relax and prepare for anaesthesia, and during surgery alongside anaesthesia to support pain control.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Pentazocine is an opioid (narcotic) analgesic that acts in the brain and nervous system to lessen pain. It provides pain relief mainly through an agonist effect at the kappa receptor, while weakly opposing the effects of opiates at the μ-receptor.

In terms of onset, its effect begins within 15 to 20 minutes when given intramuscularly or subcutaneously, and within 2 to 3 minutes when given intravenously. For distribution, it binds to plasma proteins to a moderate degree. Its metabolism takes place in the liver. As for elimination, it is cleared mainly through the kidneys, with a half-life of 2 to 3 hours.

Pregnancy & Breastfeeding

Pentazocine falls under pregnancy category C. It should be used in pregnancy only when the need is clearly established. Whether pentazocine passes into breast milk is not known, as no data are available on this.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Usual adult dose for anesthesia and moderate-to-severe pain: 30 mg by IV, IM, or subcutaneous injection, repeated every 3 to 4 hours as needed. Intravenous doses should not exceed 30 mg, and intramuscular or subcutaneous doses should not exceed 60 mg. The maximum total daily dose is 360 mg. Usual adult dose for labor pain: the most commonly used regimen is 30 mg by intramuscular injection. Alternatively, an intravenous dose of 20 mg has provided adequate pain relief for some patients once labor contractions become regular; this may be repeated two or three times at intervals of two to three hours as needed. Dose for children over 1 year of age: 0.5 mg/kg by intramuscular injection.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.