Community data Updated 2 months ago

Oxybuprocaine Hydrochloride

Ocular perioperative drugs Prescription

Indications

This eye drop briefly numbs the surface of the eye, allowing your eye pressure to be checked or a small foreign object to be safely removed.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Oxybuprocaine is a local anaesthetic that may cause somewhat less irritation than tetracaine, while acting with a similar onset and duration. It works by binding to sodium channels and reversibly stabilising the neuronal membrane, reducing its permeability to sodium ions. This inhibits depolarization of the membrane, thereby blocking the initiation and conduction of nerve impulses.

Pregnancy & Breastfeeding

Pregnancy Category C. This means either animal studies have shown some risk to the developing baby (such as birth defects or pregnancy loss), but there are no well-controlled studies in pregnant women, or no studies have been done in either humans or animals. Because of this uncertainty, the medicine should only be used during pregnancy if the expected benefit to the mother outweighs the possible risk to the unborn baby.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For short ophthalmic procedures, use a 0.4% solution. Instil 1 drop into the conjunctival sac, and tonometry can be performed after 60 seconds. A further drop, given after a 90 second interval, provides enough anaesthesia for fitting contact lenses. Giving 3 drops at 90 second intervals produces enough anaesthesia within 5 minutes to remove a foreign body from the corneal epithelium or to incise a meibomian cyst through the conjunctiva. To limit systemic absorption, press on the lacrimal sac at the medial canthus for one minute during and after instillation. Avoid use in heart block, epilepsy, impaired cardiac conduction, or myasthenia gravis, and do not apply to inflamed or infected tissue or damaged mucosa. Protect the anaesthetised eye from dust and bacterial contamination, since prolonged application can damage the cornea. Do not drive until normal vision has returned.