Indications
Olzap is indicated for the acute and maintenance treatment of schizophrenia and related psychotic disorders in which positive symptoms (such as delusions, hallucinations, disordered thinking, hostility and suspiciousness) and/or negative symptoms (such as flattened affect, emotional and social withdrawal, and poverty of speech) are prominent. Olzap is also indicated for the treatment of acute manic or mixed episodes in bipolar disorder, with or without psychotic features, and with or without a rapid cycling course.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Olanzapine is an antipsychotic medicine. It acts on a broad range of receptors in the brain, including serotonin receptors (5HT2A/2C, 5HT3, 5HT6), dopamine receptors (D1, D2, D3, D4, D5), the M1-M5 cholinergic muscarinic receptors, α1 adrenergic receptors, and histamine H1 receptors. As with other medicines used in schizophrenia, exactly how Olanzapine works is not fully understood, but its benefit is thought to come mainly from blocking dopamine and serotonin type 2 (5HT2) activity together. Taken by mouth, it is absorbed well and reaches its highest levels in the blood after 5 to 8 hours; food does not affect this absorption. Studies have not found Olanzapine to cause mutations, chromosome damage, or cancer.
Pregnancy & Breastfeeding
Olanzapine should be used in pregnancy only if the potential benefits justify the potential risk to the foetus. So, patients should be advised to notify their physician if they become pregnant or intend to become pregnant during treatment with Olanzapine. There is no report to show teratogenecity. Patients should not breast feed if they are taking Olanzapine.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.