Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago
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Indications

Fungal Infection Vaginal Candidiasis

Nystatin is an antifungal antibiotic that works against a wide range of yeasts and yeast-like fungi, including Candida albicans. It is used to prevent and treat Candida infections of the mouth, oesophagus and intestinal tract. It gives effective protection against oral candidiasis in babies born to mothers with vaginal candidiasis. It is also used to prevent Candida overgrowth during courses of broad-spectrum antibiotics.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Nystatin is an antifungal antibiotic with fungistatic or fungicidal activity against many pathogenic and nonpathogenic yeasts and fungi, including Candida albicans. It works by binding to sterols in the fungal cell membrane. This binding stops the membrane from acting as a selective barrier, so potassium and other cellular contents leak out. Nystatin is poorly absorbed from the gastrointestinal tract.

Pregnancy & Breastfeeding

Nystatin taken by mouth is barely absorbed into the bloodstream, so no special precautions are needed if you are pregnant.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Children: For intestinal and oral candidiasis (thrush), 1,00,000 units (1 ml) is dropped into the mouth four times daily. The longer the suspension stays in contact with the affected area of the mouth before it is swallowed, the greater its effect will be. For prophylaxis in the newborn, the suggested dose is 1,00,000 units (1 ml) once daily, or as prescribed by the physician. Adults: For the treatment of intestinal or esophageal candidiasis, 5,00,000 units (5 ml) is taken by mouth 3 or 4 times daily; the dose may be doubled if required. For prophylaxis of intestinal candidiasis in adults, the dose is 10,00,000 units (10 ml) daily. For prophylaxis to suppress the overgrowth of Candida albicans in patients receiving broad-spectrum antibiotic therapy, the dose is 10,00,000 units (10 ml) daily. For the treatment of dental sores and oral infection, 1,00,000 units (1 ml) of suspension is dropped into the mouth four times daily. Elderly: Older people with intestinal candidiasis who are unable to swallow tablets should be given 5,00,000 units (5 ml) of suspension four times daily.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.