Community data
Updated 2 months ago
Indications
Epam is used for sleep disturbances of various causes, including insomnia related to neurotic conditions, restlessness associated with involutional (age-related) changes, and sleep disturbances in patients with cerebrosclerosis. It is also indicated for myoclonic seizures.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Nitrazepam is a benzodiazepine closely related to diazepam. Unlike barbiturates, it allows natural, physiologic sleep by raising the hippocampus's stimulus threshold, without suppressing cortical function. Patients who sleep with nitrazepam tend to wake up feeling thoroughly rested.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Adults: Treatment of insomnia is usually started with a dose of 5 mg at night, although 2.5 mg is appropriate in elderly patients. The dose may be increased to 10 mg at night if the insomnia is severe.
Myoclonic seizures: Children (up to 30 kg of body weight) are given between 0.3 and 1.0 mg/kg/day in 3 divided doses. Treatment should be started with a lower dose than the usual recommended dosage range in order to determine tolerance and response. Dosage should be individualised for maximal beneficial effect.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.