Indications
Nidipine SR is a specific and potent calcium-channel blocker with peripheral and coronary vasodilator properties. It reduces peripheral resistance, after load and blood pressure. It is used in the prophylaxis and treatment of angina, Raynauds phenomenon, ischaemic heart disease, hypertension and heart failure.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Nifedipine belongs to the calcium-channel blocker class and works by blocking the movement of calcium ions across the membranes of muscle cells. It acts mainly on arterial blood vessels, causing them to widen, and in particular it dilates both the coronary arteries (which supply the heart) and the systemic arteries (which supply the rest of the body). This widening lowers blood pressure, and the body responds with a reflex increase in heart rate and cardiac output, driven by the sympathetic nervous system. Pressure within the pulmonary arteries also drops. At higher doses than those needed to relax the arteries, nifedipine can additionally have a direct weakening effect on the force of the heart's own muscle contractions.
Pregnancy & Breastfeeding
Nifedipine hasn't been studied thoroughly in well-controlled trials during pregnancy. For this reason, it should only be used in pregnancy if the expected benefit to the mother outweighs the possible risk to the unborn baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.