Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Mecomin tablet is indicated in peripheral neuropathy, diabetic neuropathy, alcoholic neuropathy, drug induced neuropathy, entrapment neuropathy, lumbago, intercostal neuralgia, diabetic retinopathy, multiple sclerosis, vertebral syndrome, Parkinson's disease, Alzheimar's disease and Bell's palsy. Mecomin Injection is indicated in the treatment of peripheral neuropathies and megaloblastic anemia due to vitamin B12 deficiency.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Mecobalamin is one of the two active forms of vitamin B12 in the body. Unlike cyanocobalamin, it carries a methyl group in place of the cyano group attached to its cobalt atom. It acts as a cofactor for the enzyme methionine synthase, which transfers methyl groups to convert homocysteine back into methionine. This function makes it essential for maintaining the myelin sheath, supporting normal nerve activity, forming red blood cells properly, and synthesizing DNA. Mecobalamin also supports the production of lipids needed by nerve cells, aids in regenerating axonal nerves, promotes axonal transport, and provides protective effects for the nervous system.

Pregnancy & Breastfeeding

There are no data available for mecobalamin to be used in pregnant women & lactating mother. However, since vitamin B12 is distributed into breast milk, The American Academy of Pediatrics considers its use to be usually compatible with breast feeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Tablet: Take one 0.5 mg tablet three times a day after meals. The dose should be adjusted according to the patient's age and the severity of the symptoms. Injection: For peripheral neuropathies, adults receive 1 ampoule (Mecobalamin 500 mcg) per dose, given by IM or IV injection three times a week. The dose may be adjusted depending on the patient's age and symptoms. For megaloblastic anemia, adults receive 1 ampoule (Mecobalamin 500 mcg) per dose, given by IM or IV injection three times a week. After 2 months of treatment, the dose should be reduced to a single 1 ampoule injection every 1 to 3 months as maintenance therapy. Use in children: Not recommended.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.