Indications
Lomecin is used to treat bacterial eye infections caused by germs that are sensitive to it, including bacterial conjunctivitis, blepharitis, and blepharo-conjunctivitis. It is also used to treat keratitis and corneal ulcer.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Lomefloxacin is a difluorinated quinolone. It kills bacteria and acts against a broad spectrum of organisms. It interferes with bacterial DNA processes such as initiation, elongation, and termination of replication, along with transcription, DNA repair, recombination, transposition, and the supercoiling and relaxation of DNA. Its target is a subunit of the bacterial enzyme gyrase (topoisomerase II). When the drug forms a stable complex with the whole gyrase tetramer A2B2, the enzyme's function is impaired, and sensitive bacteria are killed rapidly. Plasmid mediated transfer of resistance has not been observed so far. Cross resistance has only been reported with other quinolones, not with any other class of antibiotics.
Pregnancy & Breastfeeding
Animal studies show that after systemic use, Lomefloxacin crosses the placenta and passes into breast milk. There's no clinical data on using Lomefloxacin eye drops during human pregnancy or breastfeeding. For this reason, it should be used only if the potential benefit to the pregnant or breastfeeding woman outweighs the potential risk to the fetus or infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.