Indications
Linadus is used to treat type 2 diabetes mellitus, helping adults manage their blood sugar levels. Used alone, it is suitable for patients who cannot achieve adequate control through diet and exercise alone and who cannot take metformin because they cannot tolerate it or because it is contraindicated due to reduced kidney function. Used in combination, it may be added to metformin when diet, exercise and metformin alone fail to give adequate blood sugar control, or added to a sulphonylurea and metformin together when diet, exercise and this two drug combination fail to give adequate blood sugar control.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Linagliptin is used to improve blood sugar control in patients with type 2 diabetes mellitus. It works by inhibiting DPP-4 (dipeptidyl peptidase-4), an enzyme that breaks down the incretin hormones GLP-1 (glucagon like peptide-1) and GIP (glucose dependent insulinotropic polypeptide). By blocking this enzyme, Linagliptin raises the levels of active incretin hormones in the body. This prompts the pancreatic beta (β) cells to release more insulin when blood glucose is high, while also reducing the amount of glucagon released by the pancreatic alpha (α) cells into the circulation.
Pregnancy & Breastfeeding
Pregnancy category B: there are no well-controlled studies in pregnant women, so Linagliptin tablets should be used in pregnancy only if clearly needed. It is not known whether Linagliptin passes into breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.