Lidocaine + Prilocaine

Indications

Pain

This topical anaesthetic is used on normal, intact skin to numb the area before minor procedures, on genital mucous membranes ahead of minor surgical work, and as a pretreatment to numb the skin before infiltration anaesthesia is given.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Lidocaine and prilocaine belong to the amide group of local anaesthetics. They work by stabilising nerve cell membranes and blocking the ion movements needed to start and carry nerve impulses, which is what produces the numbing effect.

Pregnancy & Breastfeeding

Lidocaine + Prilocaine cream has not been formally proven safe for use in pregnancy, but decades of widespread clinical use have not shown any obvious harm. If a medicine is genuinely needed during pregnancy and no safer option is available, this one may be used. A small amount does pass into breast milk, but the quantity is so low that it is not generally expected to affect a nursing infant at normal treatment doses.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Adults: A thick layer of Lidocaine & Prilocaine cream is applied to intact skin and covered with an occlusive dressing. For minor dermal procedures such as intravenous cannulation and venipuncture, apply 2.5 grams of Lidocaine & Prilocaine cream over 20 to 25 cm2 of skin surface for at least 1 hour. For major dermal procedures, that is, more painful dermatological procedures involving a larger skin area, apply 2 grams of Lidocaine & Prilocaine cream per 10 cm2 of skin and allow it to remain in contact with the skin for at least 2 hours. For adult male genital skin, as an adjunct prior to local anesthetic infiltration, apply a thick layer of Lidocaine & Prilocaine cream to the skin surface for 15 minutes. Local anesthetic infiltration should be performed immediately after the cream is removed. For adult female genital mucous membranes, for minor procedures on the female external genitalia, such as removal of condylomata acuminata, and also as pretreatment for anesthetic infiltration, apply a thick layer of 5 to 10 grams of Lidocaine & Prilocaine cream for 5 to 10 minutes. Occlusion is not necessary for absorption, but it may be helpful to keep the cream in place. Patients should be lying down during application, especially if no occlusion is used. The procedure or the local anesthetic infiltration should be performed immediately after the cream is removed. Pediatric patients: the following are the maximum recommended doses, application areas and application times for Lidocaine & Prilocaine cream, based on a child's age and weight. For 0 to 3 months of age or under 5 kg, the maximum total dose is 1 gram, with a maximum application time of 1 hour. For 3 to 12 months of age and over 5 kg, the maximum total dose is 2 grams, with a maximum application time of 4 hours. For 1 to 6 years of age and over 10 kg, the maximum total dose is 10 grams, with a maximum application time of 4 hours. For 7 to 12 years of age and over 20 kg, the maximum total dose is 20 grams, with a maximum application time of 4 hours.