Adults: Ventriculography, adults: The usual adult volume for a single injection is 40 mL, with a range of 30 mL to 60 mL. This may be repeated as necessary. When combined with selective coronary arteriography, the total administered volume should not exceed 250 mL (87.5 g iodine). Pediatrics: The usual single injection dose of Iohexol 350 is 1.25 mL per kg of body weight, with a range of 1 mL/kg to 1.5 mL/kg. When multiple injections are given, the total administered dose should not exceed 5 mL/kg, up to a total volume of 250 mL of Iohexol 350.
Selective coronary arteriography: The usual adult volume for right or left coronary arteriography is 5 mL, with a range of 3 mL to 14 mL, per injection.
Aortic root and arch study when used alone: The usual adult single injection volume is 50 mL, with a range of 20 mL to 75 mL.
Pulmonary angiography, pediatrics: The usual single injection dose is 1 mL/kg of Iohexol 350.
Combined angiocardiographic procedures, multiple procedures. Adults: The maximum total volume for multiple procedures should not exceed 250 mL of 350 mg iodine/mL. Pediatrics: The maximum total dose for multiple injection procedures should not exceed 5 mL/kg, up to a total volume of 250 mL of Iohexol.
Aortography and selective visceral arteriography, adults: The usual adult volume as a single injection is 50 mL to 80 mL for the aorta, 30 mL to 60 mL for major branches including the celiac and mesenteric arteries, and 5 mL to 15 mL for the renal arteries. Repeated injections may be performed if indicated, but the total volume should not exceed 250 mL of Iohexol 350. Pediatrics: The usual single injection dose is 1.0 mL/kg of Iohexol 350 and should not exceed 5.0 mL/kg, up to a total volume of 250 mL of Iohexol 350.
CT scanning of the body. Head imaging by injection: 80 mL (28 gI) of Iohexol 350 (350 mgI/mL). Body imaging by injection: 60 mL to 100 mL (21 gI to 35 gI) of Iohexol 350 (350 mgI/mL).
Digital subtraction angiography, intravenous administration: The usual injection volume of Iohexol 350 for the intravenous digital technique is 30 mL to 50 mL. This is administered as a bolus at 7.5 to 30 mL per second using a pressure injector. The volume and rate of injection will depend primarily on the type of equipment and technique used. Frequently, three or more injections may be required, up to a total volume not to exceed 250 mL (87.5 g iodine).
Peripheral angiography: The volume required will depend on the size, flow rate, and disease state of the injected vessel and on the size and condition of the patient, as well as the imaging technique used. The dosage recommended for use in peripheral angiography is as follows. Aortofemoral runoffs: 20 mL to 70 mL of Iohexol 350 (350 mgI/mL). Selective arteriograms (femoral/iliac): 10 mL to 30 mL of Iohexol 350 (350 mgI/mL).
Excretory urography, adults: Iohexol 350 at dosages from 200 mg iodine/kg body weight to 350 mg iodine/kg body weight have produced diagnostic opacification of the excretory system in patients with normal renal function.